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OCR: ed to th The term localised myxoedema is prefer ion may of 'pretibial myxoedema' since the condi on local affect other parts of the body, depending ral forms: a pressure or trauma. It may occur in seve thema nodular form (Fig. 17.39), mimicking ery o the nodosum (which differs by being tender apitting touch); a sheet-like form with largely no oedema, coarse thickening of the skin, a hairs; and ared-violaceous discoloration, and coarse in and horny form with gross overgrowth of sk e feet and subcutaneous tissue on the dorsum of th toes. by a The affected areas are densely infiltrated ery high hyaline mucopolysaccharide material. V usually circulating levels of TSH-R antibodies a dema. present in patients with localised myxoe